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Internet explorer (version 6, 7 and 8) is impacted by a critical vulnerability leading to remote code execution and known as CVE-2012-4792. This signature is able to detect and block many variants of the proof of concept that have been publicly released. As a result, it will prevent many automated exploitations. But please notice that given the nature of this vulnerability, an advanced exploitation that bypass this protection may still be possible. Please refer to the security advices provided by Microsoft (link below) if you want to deploy complementary protections for that issue.
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